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Article

The IL12B gene is associated with asthma.

American journal of human genetics - 1 Oct 2004

Randolph Adrienne G, Lange Christoph, Silverman Edwin K, Lazarus Ross, Silverman Eric S, Raby Benjamin, Brown Alison, Ozonoff Al, Richter Brent, Weiss Scott T

Abstract excerpt

The IL12B gene on chromosome 5q31-33 encodes the p40 subunit of interleukin 12, an immunomodulatory cytokine. To test the hypothesis that the IL12B gene contains polymorphisms associated with asthma, we genotyped six haplotype-tagging polymorphisms in the IL12B gene, both in 708 children enrolled in the Childhood Asthma Management Program (CAMP) and in their parents. Using the family-based association test (FBAT)...

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Identifiers

PMID: 15322986
DOI: 10.1086/424886
PMCID: PMC1182059

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CAMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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