Article
Interactions and chaperone function of alphaA-crystallin with T5P gammaC-crystallin mutant.
Protein science : a publication of the Protein Society - 1 Sept 2004
Liang Jack J-N
Abstract excerpt
T5P gammaC-crystallin mutation is associated with Coppock-like cataract, one of the autosomal dominant congenital cataracts. It is not known why the abundant alpha-crystallin cannot prevent the mutation-related aggregation. Our previous studies indicate that the mutation changes conformation and...
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