Article
Flagella are virulence determinants of Burkholderia pseudomallei.
Infection and immunity - 1 Apr 2003
Chua K L, Chan Y Y, Gan Y H
Abstract excerpt
Burkholderia pseudomallei, a facultatively intracellular pathogen, is a flagellated and motile gram-negative bacterium and is the causative agent of melioidosis in humans. Flagella are commonly recognized as important virulence determinants expressed by bacterial pathogens since the motility phenotype imparted by these organelles often correlates with the ability of an organism to cause disease. We used a...
Topics
- Animals
- Bacterial Proteins
- Burkholderia pseudomallei
- Caenorhabditis elegans
- Flagella
- Flagellin
- Humans
- Melioidosis
- Mice
- Mice, Inbred BALB C
- Mutation
- Tumor Cells, Cultured