Article
Cable pili and the associated 22 kDa adhesin contribute to Burkholderia cenocepacia persistence in vivo.
PloS one - 1 Jan 2011
Goldberg Joanna B, Ganesan Shyamala, Comstock Adam T, Zhao Ying, Sajjan Uma S
Abstract excerpt
BACKGROUND: Infection by Burkholderia cenocepacia in cystic fibrosis (CF) patients is associated with poor clinical prognosis. Previously, we demonstrated that one of the highly transmissible strains, BC7, expresses cable pili and the associated 22 kDa adhesin, both of which contribute to BC7 binding to airway epithelial cells. However, the contribution of these factors to induce inflammation and bacterial...
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