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Article

Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4

19 Aug 2004

Abstract excerpt

BACKGROUND: S100A4 is a small Ca2+-binding protein of the S100 family with metastasis-promoting properties. Recently, secreted S100A4 protein has been shown to possess a number of functions, including induction of angiogenesis, stimulation of cell motility and neurite extension. METHODS: Cell cultures from two human osteosarcoma cell lines, OHS and its anti-S100A4 ribozyme transfected counterpart II-11b, was...

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PMID: 15318945
DOI: 10.1186/1471-2407-4-52

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