Article
S100A6 (calcyclin) enhances the sensitivity to apoptosis via the upregulation of caspase-3 activity in Hep3B cells.
Journal of cellular biochemistry - 1 Mar 2008
Joo Joung Hyuck, Yoon Sun Young, Kim Joo Heon, Paik Sang-Gi, Min Sung Ran, Lim Jong-Seok, Choe In Seong, Choi Inpyo, Kim Jae Wha
Abstract excerpt
S100A6 (calcyclin) is a small calcium-binding protein which has been implicated in several cellular processes such as cell cycle progression, cytoskeleton rearrangement, and exocytosis. Also the upregulation of S100A6 has been reported in a variety of tumors and linked to metastasis. However, exact intracellular roles of S100A6 related with apoptosis have not been clarified yet. Here we demonstrated that the...
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