Article
Genetics of allergy and allergic sensitization: common variants, rare mutations.
Current opinion in immunology - 1 Oct 2015
Bønnelykke Klaus, Sparks Rachel, Waage Johannes, Milner Joshua D
Abstract excerpt
Our understanding of the specific genetic lesions in allergy has improved in recent years due to identification of common risk variants from genome-wide association studies (GWAS) and studies of rare, monogenic diseases. Large-scale GWAS have identified novel susceptibility loci and provided information about shared genetics between allergy, related phenotypes and autoimmunity. Studies of monogenic diseases have...
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