Article
Long-term effects of sterol depletion in C. elegans: sterol content of synchronized wild-type and mutant populations.
Journal of lipid research - 1 Nov 2004
Merris Mark, Kraeft Jessica, Tint G S, Lenard John
Abstract excerpt
Three major long-term effects of sterol deprivation in Caenorhabditis elegans are described. 1) The life expectancy of sterol-deprived wild-type animals is decreased by more than 40%. Similar decreases are found in animals carrying mutations in the daf-9, daf-12, daf-16, and clk-1 genes, suggesti...
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