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Article

Hepatitis B virus capsid assembly is enhanced by naturally occurring mutation F97L.

Journal of virology - 1 Sept 2004

Ceres Pablo, Stray Stephen J, Zlotnick Adam

Abstract excerpt

In chronic hepatitis B virus (HBV) infections, one of the most common mutations to the virus occurs at amino acid 97 of the core protein, where leucine replaces either phenylalanine or isoleucine, depending on strain. This mutation correlates with changes in viral nucleic acid metabolism and/or secretion. We hypothesize that this phenotype is due in part to altered core assembly, a process required for DNA...

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Identifiers

PMID: 15308745
DOI: 10.1128/JVI.78.17.9538-9543.2004
PMCID: PMC506917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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