Article
Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus.
Journal of virology - 1 Dec 2002
Suk Fat-Moon, Lin Min-Hui, Newman Margaret, Pan Shann, Chen Sheng-Hsuan, Liu Jean-Dean, Shih Chiaho
Abstract excerpt
Mutations of human hepatitis B virus (HBV) occur frequently within the capsid (core) protein in natural infections. The most frequent mutation of the core protein in HBV from Southeast Asia occurs at amino acid 97, changing an isoleucine (I) to a leucine (L). In our systematic study of virus-host...
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