Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global Effects of Human Papillomavirus Type 18 E6/E7 in an Organotypic Keratinocyte Culture System

13 Aug 2004

Abstract excerpt

The effects of human papillomavirus type 18 (HPV-18) E6 and E7 proteins on global patterns of host gene expression in primary human keratinocytes grown in organotypic raft culture system were assessed. Primary human keratinocytes were infected with retroviruses that express the wild-type HPV-18 E6 and E7 genes from the native differentiation-dependent HPV enhancer-promoter. Total RNA was isolated from raft...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical Cancer and HPV Research
Share to Molecular Biology Techniques and Applications
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15308700
DOI: 10.1128/jvi.78.17.9041-9050.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global Effects of Human Papillomavirus Type 18 E6/E7 in an Organotypic Keratinocyte Culture SystemPMID 15308700Read ↗

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analysesSemantic proximity Read ↗

Human Papillomavirus 16 E6 and E7 Oncoproteins Alter the Abundance of Proteins Associated with DNA Damage Response, Immune Signaling and Epidermal DifferentiationSemantic proximity Read ↗

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomesSemantic proximity Read ↗

Identification of a differentiation-inducible promoter in the E7 open reading frame of human papillomavirus type 16 (HPV-16) in raft cultures of a new cell line containing high copy numbers of episomal HPV-16 DNASemantic proximity Read ↗

Changes in global gene expression profiles induced by HPV 16 E6 oncoprotein variants in cervical carcinoma C33-A cellsSemantic proximity Read ↗

Individual and Complementary Effects of Human Papillomavirus Oncogenes on Epithelial Cell Proliferation and Differentiation.Semantic proximity Read ↗

Expression of human papillomavirus type 16 E7 oncoprotein alters keratinocytes expression profile in response to tumor necrosis factor-αSemantic proximity Read ↗

Protein profiling and identification of modulators regulated by the E7 oncogene in the C33A cell line by proteomics and genomicsSemantic proximity Read ↗

A new cell culture model to genetically dissect the complete human papillomavirus life cycleSemantic proximity Read ↗

The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18Semantic proximity Read ↗

Oncogenic potential diverge among human papillomavirus type 16 natural variants.Semantic proximity Read ↗

Role of the E1 <sup>∧</sup> E4 Protein in the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 31Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.