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Article

Role of the E1 <sup>∧</sup> E4 Protein in the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 31

12 May 2005

Abstract excerpt

The most highly expressed protein in the productive life cycle of human papillomaviruses (HPVs) is E1--E4, but its function is not well understood. To investigate the role of E1--E4, we undertook a genetic analysis in the context of the complete HPV type 31 (HPV31) genome. A mutant HPV31 genome (E4M9) was constructed that contained a stop codon in the E4 open reading frame at amino acid 9 and was silent in the...

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Identifiers

PMID: 15890911
DOI: 10.1128/jvi.79.11.6732-6740.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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