Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of human papillomavirus type 16 E7 oncoprotein alters keratinocytes expression profile in response to tumor necrosis factor-α

30 Dec 2009

Abstract excerpt

Acute expression of E7 oncogene from human papillomavirus (HPV) 16 or HPV18 is sufficient to overcome tumor necrosis factor (TNF)-alpha cytostatic effect on primary human keratinocytes. In the present study, we investigated the molecular basis of E7-induced TNF resistance through a comparative analysis of the effect of this cytokine on the proliferation and global gene expression of normal and E7-expressing...

Topics

Join the communities discussing this publication.

Cancer-related Molecular Pathways
Cervical Cancer and HPV Research
NF-κB Signaling Pathways

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20042637
DOI: 10.1093/carcin/bgp333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of human papillomavirus type 16 E7 oncoprotein alters keratinocytes expression profile in response to tumor necrosis factor-αPMID 20042637Read ↗

The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosisSemantic proximity Read ↗

HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transitionSemantic proximity Read ↗

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 OncoproteinsSemantic proximity Read ↗

Systematic analysis of IL-1 cytokine signaling by high-risk HPV oncoproteinsSemantic proximity Read ↗

Digital RNA Sequencing of Human Epidermal Keratinocytes Carrying Human Papillomavirus Type 16 E7Semantic proximity Read ↗

Oncogenic potential diverge among human papillomavirus type 16 natural variants.Semantic proximity Read ↗

Human Papillomavirus 16 E6 and E7 Oncoproteins Alter the Abundance of Proteins Associated with DNA Damage Response, Immune Signaling and Epidermal DifferentiationSemantic proximity Read ↗

Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivationSemantic proximity Read ↗

The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune responseSemantic proximity Read ↗

Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of NotchSemantic proximity Read ↗

The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathwaySemantic proximity Read ↗

HPV-Mediated Resistance to TNF and TRAIL Is Characterized by Global Alterations in Apoptosis Regulatory Factors, Dysregulation of Death Receptors, and Induction of ROS/RNSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.