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Article

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes

1 Oct 1992

Abstract excerpt

The expression of viral genes during the productive life cycle of human papillomaviruses (HPV) is tightly coupled to the differentiation program of epithelial cells. We have examined transcription of HPV as a function of differentiation in an in vitro organotypic raft culture system which allows for epithelial stratification at the air-liquid interface. When CIN612 cells, which contain episomal copies of HPV type...

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PMID: 1326657
DOI: 10.1128/jvi.66.10.6070-6080.1992

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