Article
Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling.
The Journal of biological chemistry - 22 Oct 2004
DellaVecchia Matthew J, Croteau Deborah L, Skorvaga Milan, Dezhurov Sergey V, Lavrik Olga I, Van Houten Bennett
Abstract excerpt
To better define the molecular architecture of nucleotide excision repair intermediates it is necessary to identify the specific domains of UvrA, UvrB, and UvrC that are in close proximity to DNA damage during the repair process. One key step of nucleotide excision repair that is poorly understood is the transfer of damaged DNA from UvrA to UvrB, prior to incision by UvrC. To study this transfer, we have utilized...
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