Article
DNA binding by an amino acid residue in the C-terminal half of the Rel homology region.
Chemistry & biology - 1 Sept 1994
Liu J, Fan Q R, Sodeoka M, Lane W S, Verdine G L
Abstract excerpt
BACKGROUND: Members of the Rel family of transcription factors are important in regulating the inflammatory, acute phase, and immune responses in mammals. The structural basis for sequence-specific binding by Rel proteins is poorly understood, however. In the studies reported here, a new photoaff...
Topics
- Amino Acids
- Cross-Linking Reagents
- DNA
- Mutation
- NF-kappa B
- Photoaffinity Labels
- Sequence Homology, Nucleic Acid