Article
The original shaker-with-syndactylism mutation (sy) is a contiguous gene deletion syndrome.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 1998
Johnson K R, Cook S A, Zheng Q Y
Abstract excerpt
Tests for allelism among mice with four different mutant alleles at the shaker-with-syndactylism locus on mouse Chromosome (Chr) 18 provide evidence that the original radiation-induced mutation, sy, is a deletion including at least two genes associated with distinct phenotypes. Mice homozygous fo...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Deafness
- Gene Deletion
- Genetic Complementation Test
- Genetic Markers
- Humans
- Limb Deformities, Congenital
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Neurologic Mutants
- Syndactyly
- Vestibule, Labyrinth