Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Old yellow enzyme protects the actin cytoskeleton from oxidative stress.

Molecular biology of the cell - 1 Oct 2004

Haarer Brian K, Amberg David C

Abstract excerpt

Old Yellow Enzyme (OYE) has long served as a paradigm for the study of flavin-containing NADPH oxido-reductases and yet its physiological role has remained a mystery. A two-hybrid interaction between Oye2p and actin led us to investigate a possible function in the actin cytoskeleton. We found that oye deletion strains have an overly elaborate actin cytoskeleton that cannot be attributed to changes in actin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Two-Hybrid System Techniques
Share to Actins
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disulfides

Share to NADPH Dehydrogenase

Share to Oxidation-Reduction

Share to Oxidative Stress

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15304519
DOI: 10.1091/mbc.e04-06-0445
PMCID: PMC519146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Old yellow enzyme protects the actin cytoskeleton from oxidative stress.PMID 15304519Read ↗

Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast.Semantic proximity Read ↗

Characterization of YqjM, an Old Yellow Enzyme Homolog from Bacillus subtilis Involved in the Oxidative Stress ResponseSemantic proximity Read ↗

A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast.Semantic proximity Read ↗

Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism.Semantic proximity Read ↗

A Peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanismsSemantic proximity Read ↗

Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast.Semantic proximity Read ↗

Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast.Semantic proximity Read ↗

Comprehensive genome-wide analysis reveals different classes of enigmatic old yellow enzyme in fungi.Semantic proximity Read ↗

Metabolic response to Parkinson’s disease recapitulated by the haploinsufficient phenotype of diploid yeast cells hemizygous for the adrenodoxin reductase geneSemantic proximity Read ↗

Oxidative damage to proteins in yeast cells exposed to adaptive levels of H(2)O(2).Semantic proximity Read ↗

Probing interactions of the Escherichia coli F0F1 ATP synthase beta and gamma subunits with disulphide cross-links.Semantic proximity Read ↗

Dual targeted poplar ferredoxin NADP(+) oxidoreductase interacts with hemoglobin 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.