Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast.

Journal of cell science - 15 May 2005

Gourlay Campbell W, Ayscough Kathryn R

Abstract excerpt

The build up of reactive oxygen species (ROS) is known to contribute to a reduction in the lifespan of a cell and to their degeneration in diseases such as Alzheimer's and tissue ischaemia. It is therefore important to elucidate pathways that regulate cellular oxidative stress. We have previously shown that actin dynamics can affect the oxidative-stress burden on a yeast cell and thereby its potential lifespan....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Cyclic AMP
Share to Cytoskeletal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeleton

Share to Endosomal Sorting Complexes Required for Transport

Share to Phosphoric Diester Hydrolases

Share to Reactive Oxygen Species

Share to Ubiquitin-Protein Ligase Complexes

Source

Identifiers

PMID: 15855235
DOI: 10.1242/jcs.02337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast.PMID 15855235Read ↗

The actin cytoskeleton, RAS-cAMP signaling and mitochondrial ROS in yeast apoptosis.Semantic proximity Read ↗

Actin-induced hyperactivation of the Ras signaling pathway leads to apoptosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast.Semantic proximity Read ↗

Gene-dependent yeast cell death pathway requires AP-3 vesicle trafficking leading to vacuole membrane permeabilizationSemantic proximity Read ↗

Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast.Semantic proximity Read ↗

TOR complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species.Semantic proximity Read ↗

A Peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanismsSemantic proximity Read ↗

Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress.Semantic proximity Read ↗

Ras pathway signaling accelerates programmed cell death in the pathogenic fungus Candida albicans.Semantic proximity Read ↗

The actin cytoskeleton: a key regulator of apoptosis and ageing?Semantic proximity Read ↗

Old yellow enzyme protects the actin cytoskeleton from oxidative stress.Semantic proximity Read ↗

Molecular phenotyping of aging in single yeast cells using a novel microfluidic device.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.