Article
Cytotoxic T lymphocyte antigen 4 heterozygous codon 49 A/G dimorphism is associated to latent autoimmune diabetes in adults (LADA).
Autoimmunity - 1 Jun 2005
Caputo Mariela, Cerrone Gloria Edith, López Ariel Pablo, Villalba Anabel, Krochik Gabriela Andrea, Cédola Federico Norberto, Targovnik Héctor Manuel, Frechtel Gustavo Daniel
Abstract excerpt
Autoimmune diabetes is an organ specific and multifactorial disorder with a classical onset as insulin dependent diabetes mellitus (IDDM) and with another form of onset as latent autoimmune diabetes in adults (LADA), which has a slower onset and a later progress to insulin dependency as a result of the beta cells destruction. The cytotoxic T lymphocyte-antigen 4 (CTLA4) has been identified as a susceptible marker...
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