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Article

Improvement of arachidonic acid production by mutants with lower n-3 desaturation activity derived from Mortierella alpina.

Applied microbiology and biotechnology - 1 Dec 2004

Sakuradani Eiji, Hirano Yuriko, Kamada Nozomu, Nojiri Masutoshi, Ogawa Jun, Shimizu Sakayu

Abstract excerpt

Five mutants were obtained, Y11, Y135, Y164, Y180 and Y61, capable of accumulating higher amounts of arachidonic acid (AA) than Mortierella alpina 1S-4, an industrial strain for the production of AA-rich triacylglycerol (TG). This is thought to be due to low or no activity of n-3 desaturation with conversion of AA to eicosapentaenoic acid, which functions at a cultural temperature below 20 degrees C. In...

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PMID: 15300418
DOI: 10.1007/s00253-004-1682-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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