Article
Identification of mutation sites on omega3 desaturase genes from Mortierella alpina 1S-4 mutants.
Journal of bioscience and bioengineering - 1 Jan 2009
Sakuradani Eiji, Abe Takahiro, Shimizu Sakayu
Abstract excerpt
The mutation sites on omega3 desaturase genes in two omega3 desaturase-defective mutants derived from arachidonic acid-producing Mortierella alpina 1S-4 were identified. The mutations each resulted in an amino acid replacement (W232Stop or W386Stop) which caused a lack of omega3 desaturase activity in these mutants.
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