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Article

Identification of mutation sites on Delta12 desaturase genes from Mortierella alpina 1S-4 mutants.

Journal of bioscience and bioengineering - 1 Feb 2009

Sakuradani Eiji, Abe Takahiro, Matsumura Kenji, Tomi Akiko, Shimizu Sakayu

Abstract excerpt

The mutation sites on the Delta12 desaturase gene in Mortierella alpina Delta12 desaturase-defective mutants SR88, TM912, and Mut48 accumulating Mead acid were identified. Each mutation resulted in an amino acid replacement (H116Y and P166L) in the Delta12 desaturase gene from SR88 and Mut48, respectively.

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PMID: 19217543
DOI: 10.1016/j.jbiosc.2008.10.011

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