Article
Mechanical distention modulates alveolar epithelial cell phenotypic expression by transcriptional regulation.
American journal of respiratory cell and molecular biology - 1 Aug 1999
Gutierrez J A, Ertsey R, Scavo L M, Collins E, Dobbs L G
Abstract excerpt
The development of a normal pulmonary alveolar epithelium, essential for gas exchange, is critical for the successful adaptation to extrauterine life. From observations of natural and experimental developmental abnormalities, it has been hypothesized that mechanical factors may play a role in regulating differentiation of the pulmonary alveolar epithelium. To test this hypothesis directly, we have investigated...
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