Article
Changes in alveolar epithelial cell proportions during fetal and postnatal development in sheep.
American journal of physiology. Lung cellular and molecular physiology - 1 Sept 2003
Flecknoe S J, Wallace M J, Cock M L, Harding R, Hooper S B
Abstract excerpt
Basal lung expansion is an important determinant of alveolar epithelial cell (AEC) phenotype in the fetus. Because basal lung expansion increases toward term and is reduced after birth, we hypothesized that these changes would be associated with altered proportions of AECs. AEC proportions were calculated with electron microscopy in fetal and postnatal sheep. Type I AECs increased from 4.8 +/- 1.3% at 91 days to...
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