Haplotype inference by maximum parsimony.

doi:10.1093/bioinformatics/btg239

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Article

Haplotype inference by maximum parsimony.

Bioinformatics (Oxford, England) - 22 Sept 2003

Wang Lusheng, Xu Ying

Abstract excerpt

MOTIVATION: Haplotypes have been attracting increasing attention because of their importance in analysis of many fine-scale molecular-genetics data. Since direct sequencing of haplotype via experimental methods is both time-consuming and expensive, haplotype inference methods that infer haplotypes based on genotype samples become attractive alternatives. RESULTS: (1) We design and implement an algorithm for an...

Topics

Algorithms
Gene Expression Profiling
Gene Frequency
Haplotypes
Humans
Linkage Disequilibrium
Models, Genetic
Polymorphism, Single Nucleotide
Receptors, Adrenergic, beta-2
Recombination, Genetic
Reproducibility of Results
Sensitivity and Specificity
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 14512348
DOI: 10.1093/bioinformatics/btg239

Provenance

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