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Article

Detection of hepatitis B virus core mutants by PCR-RFLP in chronically infected patients.

Journal of virological methods - 15 Sept 2004

Barros M F, Rodrigues P A, Matias S R, Carreira L M, Machado-Caetano J A

Abstract excerpt

HBV chronic infection is an important health problem. The HBV core antigen carries several epitopes for T and B cell recognition and the immune response is crucial for determining the outcome of viral infection. Using PCR-RFLP several point mutations were detected in the HBV core ORF of HBV extracted from the serum of 140 chronically infected patients and 86 samples from another 37 patients followed-up in a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Point Mutation

Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 15288954
DOI: 10.1016/j.jviromet.2004.03.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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