Article
Identification of hepatitis B virus core mutants by PCR-RFLP in chronic hepatitis B patients from Punjab, Pakistan.
Archives of virology - 1 Jan 2008
Aslam M A, Awan F R, Tauseef I, Ali S, Ahmad N, Malik N A, Riaz M N, Qureshi J A
Abstract excerpt
Chronic hepatitis B virus (HBV) infection remains a major health issue worldwide. Several factors including core gene variation are responsible for the development of chronicity of HBV infection. The present study was designed to identify the variations in the core region of the HBV genome in a local population of chronic hepatitis B patients (n = 57) using a PCR-based restriction fragment length polymorphism...
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