Article
CD31+ cells represent highly angiogenic and vasculogenic cells in bone marrow: novel role of nonendothelial CD31+ cells in neovascularization and their therapeutic effects on ischemic vascular disease.
Circulation research - 3 Sept 2010
Kim Hyongbum, Cho Hyun-Jai, Kim Sung-Whan, Liu Bianling, Choi Yong Jin, Lee JiYoon, Sohn Young-Doug, Lee Min-Young, Houge Mackenzie A, Yoon Young-sup
Abstract excerpt
RATIONALE: Bone marrow (BM) cells play an important role in physiological and therapeutic neovascularization. However, it remains unclear whether any specific uncultured BM cell populations have higher angiogenic and vasculogenic activities. Moreover, there has been controversy regarding the vasculogenic ability of BM cells. OBJECTIVE: Preliminary flow cytometric analysis showed that CD31, traditionally a marker...
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