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Article

Phenotypic and functional changes of circulating monocytes and polymorphonuclear leucocytes from elderly persons.

Immunology and cell biology - 1 Aug 2004

De Martinis Massimo, Modesti Marco, Ginaldi Lia

Abstract excerpt

The function and phenotype of monocytes and granulocytes in the elderly is consistently remodelled. Because leucocyte adhesion molecules play important roles in mediating a wide variety of leucocyte functions, age-related changes in their expression on granulocyte and monocyte surfaces could be partially responsible for immune dysfunctions during senescence. Considering the central role of innate immunity in the...

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Identifiers

PMID: 15283852
DOI: 10.1111/j.0818-9641.2004.01242.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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