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Article

LDL accelerates monocyte to macrophage differentiation: Effects on adhesion and anoikis.

Atherosclerosis - 1 Mar 2016

Escate R, Padro T, Badimon L

Abstract excerpt

BACKGROUND AND AIMS: High LDL triggers dyslipidemia and atherosclerosis, a chronic inflammatory disease with participation of the innate immunity system. Monocytes are recruited to areas of LDL-induced endothelial damage and initiate differentiation. This study was aimed to investigate the effects of LDL on the early transitional stages of monocyte differentiation into macrophages. METHODS: Blood monocytes,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26800307
DOI: 10.1016/j.atherosclerosis.2016.01.002

Genes

CASP3
CASP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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