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Pangenomic decomposition reveals lineage-specific immune-evasion and virulence architectures in group A <i>Streptococcus</i>

2026-05-27

Abstract excerpt

Streptococcus pyogenes (group A Streptococcus , GAS) causes over 700 million infections annually and has resurged globally as a cause of invasive disease. However, the genomic basis by which distinct GAS lineages produce diverse clinical phenotypes remains incompletely understood. Here, we analyzed 399 quality-controlled complete genomes spanning 103 emm types and 27 countries and applied non-negative matrix fac...

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Literature Corpus work
c1a5c12f-d16d-5d54-9e83-015fff07198b
DOI
10.64898/2026.05.26.728020
Open publication

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Pangenomic decomposition reveals lineage-specific immune-evasion and virulence architectures in group A <i>Streptococcus</i>DOI 10.64898/2026.05.26.728020
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