Article
Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics.
Proceedings of the National Academy of Sciences of the United States of America - 2 Mar 2010
Beres Stephen B, Carroll Ronan K, Shea Patrick R, Sitkiewicz Izabela, Martinez-Gutierrez Juan Carlos, Low Donald E, McGeer Allison, Willey Barbara M, Green Karen, Tyrrell Gregory J, Goldman Thomas D, Feldgarden Michael, Birren Bruce W, Fofanov Yuriy, Boos John, Wheaton William D, Honisch Christiane, Musser James M
Abstract excerpt
Understanding the fine-structure molecular architecture of bacterial epidemics has been a long-sought goal of infectious disease research. We used short-read-length DNA sequencing coupled with mass spectroscopy analysis of SNPs to study the molecular pathogenomics of three successive epidemics of...
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