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Article

A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor.

AIDS (London, England) - 20 Aug 2004

Zhao Xiu-Ying, Lee Shui-Shan, Wong Ka-Hing, Chan Kenny Chi-Wai, He Zhi-Min, Ma Selene, Ng Fai, Chan Chris Chung-Sing, Ho Tina, Ng Mun-Hon, Zheng Bo-Jian

Abstract excerpt

A Nepalese heterozygous carrier of a CCR5 mutant, designated 118delF, was characterized. There was a 3 basepair deletion at 352-354 in the CCR5 open reading frame, resulting in the deletion of the phe-118 residue located in the third transmembrane domain. The mutant protein has retained antigen s...

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Source

Identifiers

PMID: 15280786
DOI: 10.1097/01.aids.0000131382.15232.dc

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15280786-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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