Article
Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG.
The Annals of thoracic surgery - 1 Aug 2004
MacKensen G Burkhard, Swaminathan Madhav, Ti Lian K, Grocott Hilary P, Phillips-Bute Barbara G, Mathew Joseph P, Newman Mark F, Milano Carmelo A, Stafford-Smith Mark
Abstract excerpt
BACKGROUND: Renal dysfunction is a serious complication of cardiac surgery that is highly associated with short- and long-term adverse outcome. While the apolipoprotein E (APOE) epsilon4 allele has been linked to the occurrence of both postcardiac surgery acute renal injury (epsilon4 favorable) and ascending aortic arteriosclerosis (epsilon4 unfavorable), the role of epsilon4 in the relationship between these two...
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