Article
Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients.
Anesthesiology - 1 Aug 2000
Chew S T, Newman M F, White W D, Conlon P J, Saunders A M, Strittmatter W J, Landolfo K, Grocott H P, Stafford-Smith M
Abstract excerpt
BACKGROUND: Renal dysfunction after cardiac surgery occurs in up to 8% of patients and is associated with major increases in morbidity, mortality, and cost. Genetic polymorphisms have been implicated as a factor in the progression of chronic renal disease, but a genetic basis for the development of acute renal impairment has not been investigated. The authors therefore tested the hypothesis that apolipoprotein E...
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