Article
Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.
Kidney international - 1 Oct 2015
Stafford-Smith Mark, Li Yi-Ju, Mathew Joseph P, Li Yen-Wei, Ji Yunqi, Phillips-Bute Barbara G, Milano Carmelo A, Newman Mark F, Kraus William E, Kertai Miklos D, Shah Svati H, Podgoreanu Mihai V
Abstract excerpt
Acute kidney injury (AKI) is a common, serious complication of cardiac surgery. Since prior studies have supported a genetic basis for postoperative AKI, we conducted a genome-wide association study (GWAS) for AKI following coronary bypass graft (CABG) surgery. The discovery data set consisted of 873 nonemergent CABG surgery patients with cardiopulmonary bypass (PEGASUS), while a replication data set had 380...
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