Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during <i>Drosophila melanogaster</i> oogenesis

Abstract excerpt

A complex relationship exists between autophagy and apoptosis, but the regulatory mechanisms underlying their interactions are largely unknown. We conducted a systematic study of Drosophila melanogaster cell death-related genes to determine their requirement in the regulation of starvation-induced autophagy. We discovered that six cell death genes--death caspase-1 (Dcp-1), hid, Bruce, Buffy, debcl, and p53-as...

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