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Article

Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing.

Antimicrobial agents and chemotherapy - 1 Aug 2004

Rhee Soo-Yon, Liu Tommy, Ravela Jaideep, Gonzales Matthew J, Shafer Robert W

Abstract excerpt

In a sample of 6,156 sequences from 4,183 persons, the top 30 patterns of protease inhibitor, nucleoside reverse transcriptase (RT) inhibitor, and nonnucleoside RT inhibitor mutations accounted for 55, 46, and 66%, respectively, of sequences with drug resistance mutations. Characterization of the phenotypic and clinical significance of these common patterns may lead to improved treatment recommendations for a...

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Identifiers

PMID: 15273130
DOI: 10.1128/AAC.48.8.3122-3126.2004
PMCID: PMC478552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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