Article
Temporal Trends in HIV-1 Mutations Used for the Surveillance of Transmitted Drug Resistance.
Viruses - 11 May 2021
Rhee Soo-Yon, Tzou Philip L, Shafer Robert W
Abstract excerpt
In 2009, a list of nonpolymorphic HIV-1 drug resistance mutations (DRMs), called surveillance DRMs (SDRMs), was created to monitor transmitted drug resistance (TDR). Since 2009, TDR increased and antiretroviral therapy (ART) practices changed. We examined the changing prevalence of SDRMs and identified candidate SDRMs defined as nonpolymorphic DRMs present on ≥ 1 expert DRM list and in ≥0.1% of ART-experienced...
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