Article
Genotypic testing for human immunodeficiency virus type 1 drug resistance.
Clinical microbiology reviews - 1 Apr 2002
Shafer Robert W
Abstract excerpt
There are 16 approved human immunodeficiency virus type 1 (HIV-1) drugs belonging to three mechanistic classes: protease inhibitors, nucleoside and nucleotide reverse transcriptase (RT) inhibitors, and nonnucleoside RT inhibitors. HIV-1 resistance to these drugs is caused by mutations in the prot...
Topics
- Anti-HIV Agents
- Drug Resistance, Viral
- Drug Therapy, Combination
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Microbial Sensitivity Tests
- Reverse Transcriptase Inhibitors
