Article
Regulation of the expression of cell wall stress stimulon member gene msrA1 in methicillin-susceptible or -resistant Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 Aug 2004
Pechous Roger, Ledala Nagender, Wilkinson Brian J, Jayaswal Radheshyam K
Abstract excerpt
Genome-wide transcriptional profiling studies of the response of Staphylococcus aureus to cell wall-active antibiotics have led to the discovery of a cell wall stress stimulon of genes induced by these agents. msrA1, encoding methionine sulfoxide reductase, is a highly induced member gene of this stimulon. In the present study we show that msrA1 induction by oxacillin is common to all methicillin-susceptible...
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