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The Staphylococcus aureus Thiol/Oxidative Stress Global Regulator Spx Controls <i>trfA</i> , a Gene Implicated in Cell Wall Antibiotic Resistance

30 Apr 2013

Abstract excerpt

S. aureus combats cell wall antibiotic stress by altered gene expression mediated by various environmental signal sensors. In this study, we examined the transcriptional regulation of trfA, a gene related to mecA of Bacillus subtilis encoding an adaptor protein implicated in multiple roles, notably, proteolysis and genetic competence. Despite strong sequence similarity to B. subtilis mecA, the function of S....

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PMID: 23629700
DOI: 10.1128/aac.00220-13

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