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Article

Crystallization and preliminary crystallographic analysis of endonuclease VIII in its uncomplexed form.

Acta crystallographica. Section D, Biological crystallography - 1 Aug 2004

Golan Gali, Zharkov Dmitry O, Fernandes Andrea S, Zaika Elena, Kycia Jadwiga H, Wawrzak Zdzislaw, Grollman Arthur P, Shoham Gil

Abstract excerpt

The Escherichia coli DNA repair enzyme endonuclease VIII (EndoVIII or Nei) excises oxidized pyrimidines from damaged DNA substrates. It overlaps in substrate specificity with endonuclease III and may serve as a back-up for this enzyme in E. coli. The three-dimensional structure of Nei covalently complexed with DNA has been recently determined, revealing the critical amino-acid residues required for DNA binding...

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PMID: 15272182
DOI: 10.1107/S0907444904013241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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