Article
Loss of heterozygosity patterns of sclerosing hemangioma of the lung and bronchioloalveolar carcinoma indicate a similar molecular pathogenesis.
Archives of pathology & laboratory medicine - 1 Aug 2004
Dacic Sanja, Sasatomi Eizaburo, Swalsky Patricia A, Kim Dong Won, Finkelstein Sydney D, Yousem Samuel A
Abstract excerpt
CONTEXT: The histogenesis and origin of sclerosing hemangioma (SH) of lung were uncertain for many years. Many immunohistochemical, ultrastructural, and recent molecular studies support the hypothesis that SH is a neoplasm originating from the cells of the terminal lobular unit, similar to the nonmucinous variant of bronchioloalveolar carcinoma (BAC). Most cases of SH are benign, but they can metastasize to the...
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