Article
MUC1 and the MUCs: A Family of Human Mucins with Impact in Cancer Biology
1 Jan 2004
Abstract excerpt
Mucins represent a family of glycoproteins characterized by repeat domains and a dense O-glycosylation. During the last two decades, the gene and peptide structures of various mucins as well as their glycosylation states were partly elucidated. Characteristic tumor-associated alterations of the expression patterns and glycosylation profiles were observed in biochemical, immunochemical, and histological studies...
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