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Mucins in Gastric Cancer - An Update

1 Jan 2013

Abstract excerpt

Mucins are high-molecular-weight glycoproteins expressed throughout the gastrointestinal tract, with a key role in mucosal protection and function. In gastric cancer expression of MUC5AC and MUC1 is reduced and denovo expression of MUC2 occurs. With progressive loss of tumor differentiation and increased tumor stage, expression of MUC5AC and MUC1 is further reduced, and MUC2 decreases. Isolated MUC2 expression...

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PMID: 24077811
DOI: 10.4172/2161-069x.1000123

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