Article
The functional role of blood platelet components in angiogenesis.
Thrombosis and haemostasis - 1 Aug 2004
Rhee Joong-Sup, Black Martin, Schubert Uwe, Fischer Silvia, Morgenstern Eberhard, Hammes Hans-Peter, Preissner Klaus T
Abstract excerpt
The process of neovascularization greatly depends on the induction of the angiogenic phenotype of endothelial cells that is strictly controlled by humoral factors as well as by cellular communications in the vascular system. Although blood platelets contain several secretable pro- and antiangiogenic components, their overall role in angiogenesis remains poorly understood. In a mouse model of hypoxia-induced...
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