Article
Genomic profiling of interpopulation diversity guides prioritization of candidate-genes for autoimmunity.
Genes and immunity - 1 Sept 2004
Grossman I, Avidan N, Singer C, Paperna T, Lancet D, Beckmann J S, Miller A
Abstract excerpt
Autoimmune diseases seem to have strong genetic attributes, and are affected to some extent by shared susceptibility loci. The latter potentially amount to hundreds of candidate genes (CG), creating the need for a prioritization strategy in genetic association studies. To form such a strategy, 26 autoimmune-related CG were genotyped for a total of 72 single nucleotide polymorphisms (SNPs) in three distinct...
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