Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary dynamics of human autoimmune disease genes and malfunctioned immunological genes.

BMC evolutionary biology - 25 Jan 2012

Podder Soumita, Ghosh Tapash Chandra

Abstract excerpt

BACKGROUND: One of the main issues of molecular evolution is to divulge the principles in dictating the evolutionary rate differences among various gene classes. Immunological genes have received considerable attention in evolutionary biology as candidates for local adaptation and for studying functionally important polymorphisms. The normal structure and function of immunological genes will be distorted when...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Autoimmune Diseases
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Genome, Human

Share to Immune System Diseases

Share to Multivariate Analysis

Share to Principal Component Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 22276655
DOI: 10.1186/1471-2148-12-10
PMCID: PMC3347981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary dynamics of human autoimmune disease genes and malfunctioned immunological genes.PMID 22276655Read ↗

Genetic Factors of Autoimmune DiseasesSemantic proximity Read ↗

Ancient DNA reveals evolutionary origins of autoimmune diseasesSemantic proximity Read ↗

Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism.Semantic proximity Read ↗

Major histocompatibility complex genomics and human disease.Semantic proximity Read ↗

Conserved and quickly evolving immunome genes have different evolutionary paths.Semantic proximity Read ↗

Genetic background for immune-mediated diseases.Semantic proximity Read ↗

A computational framework to find novel therapeutics for autoimmunitySemantic proximity Read ↗

The effect of immunogenetic variability on human health : bioinformatics investigations from different perspectivesSemantic proximity Read ↗

Human MHC architecture and evolution: implications for disease association studies.Semantic proximity Read ↗

Immunogenetics and genomics.Semantic proximity Read ↗

Integrative analyses of leprosy susceptibility genes indicate a common autoimmune profile.Semantic proximity Read ↗

Heterogeneity-mediated cellular adaptation and its trade-off: searching for the general principles of diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.